Fantasy Football Help?

I have the first pick in this Sundays draft. It is a 2 QB start league where a TD is 6 pts for QB's also. Its also a PPR league for half a point per. QB,QB, RB, RB, WR, WR Flex WR/RB TE, K, DEF is the starting lineup. Should I go RB (AP, MJD or Forte) since there is an extra RB slot or go QB (Brees, Brady) since i have to start two and they will go quick. Any advice would be great...this is my first time playing...thanks.